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    • Health Article References

    Is Low GABA Why I Feel The Way I Do?

    We have listed all references noted below for the health article Is Low GABA Why I Feel The Way I Do? for your convenience below.

    1. Shimada, M., et al. Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study. Clin Exp Hypertens. 31(4):342-354, 2009
    2. Abdou, A. M., et al. Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 26(3):201-208, 2006
    3. Shell, W., et al. A randomized, placebo-controlled trial of an amino acid preparation on timing and quality of sleep. Am J Ther. 17(2):133-139, 2010
    4. Head, K. A., et al. Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep. Alternative Medicine Review. 14(2), 2009
    5. Nakagawa, T., et al. Protective effects of gamma-aminobutyric acid in rats with streptozotocin-induced diabetes. J Nutr Sci Vitaminol (Tokyo). 51(4):278-282, 2005
    6. During, M. J., et al. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet. 341(8861):1607-1610, 1993
    7. Bhagwagar, Z., et al. Low GABA concentrations in occipital cortex and anterior cingulate cortex in medication-free, recovered depressed patients. Int J Neuropsychopharmacol. 11:1-6, 2007
    8. Backstrom, T., et al. Pathogenesis in menstrual cycle-linked CNS disorders. Ann N Y Acad Sci. 1007:42-53, 2003
    9. Loeb, C., et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Research. 1(3):209-212, 1987
    10. Goddard, A. W., et al. Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Arch Gen Psychiatry. 58(6):556-561, 2001
    11. Monograph: Gamma-aminobutyric acid (GABA). Alternative Medicine Review. 12(3):274-279, 2007
    12. Epperson, C. N., et al. Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study. Psychopharmacology (Berl). 186(3):425-433, 2006
    13. Ito, K., et al. GABA-synthesizing enzyme, GAD67, from dermal fibroblasts: evidence for a new skin function. Biochim Biophys Acta. 2006

    The Natural Way To Increase GABA

    These references are noted on our health article The Natural Way To Increase GABA

    1. Abdou, A. M., et al. Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 26(3):201-208, 2006.
    2. Shell, W., et al. A randomized, placebo-controlled trial of an amino acid preparation on timing and quality of sleep. Am J Ther. 17(2):133-139, 2010.
    3. Head, K. A., et al. Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep. Alternative Medicine Review. 14(2), 2009.
    4. Breier, A., et al. The GABA-A/Benzodiazepine receptor: implications for the molecular basis of anxiety. Journal of Psychiatric Research. 24(Supplement 2):91-104, 1990.
    5. Nemeroff, C. B., et al. The role of GABA in the pathophysiology and treatment of anxiety disorders. Psychopharmacol Bull. 37(4):133-146, 2003.
    6. El Idrissi, A.. Taurine improves learning and retention in aged mice. Neurosci Lett. 2008.
    7. Molchanova, S. M., et al. Effect of taurine on the concentrations of glutamate, GABA, glutamine and alanine in the rat striatum and hippocampus. Proc West Pharmacol Soc. 50:95-97, 2007.
    8. Kimura R, Murata T. Influence of alkylamides of glutamic acid and related compounds on the central nervous system I. Central depressant effect of theanine. Chem Pharm Bull. 19:1257–1261, 1971.
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    13. Ito, K., et al. Effects of L-theanine on the release of alpha brain waves in human volunteers. Nippon Nogeikagaku Kaishi. 72:153-157, 1998.
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    28. Akhondzadeh, S., et al. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxezepam. J Clin Pharm Ther. 26(5):363-367, 2001.
    29. Brown, E., et al. Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA J. 75(5):333-337, 2007.
    30. Dhawan, K., et al. Anxiolytic activity of aerial and underground parts of Passiflora incarnata. Fitoterapia. 72(8):922-926, 2001.
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    40. Nick, G. L. Inositol as a treatment for psychiatric disorders: a scientific evaluation of its clinical effectiveness. Townsend Letter for Doctors and Patients. October 2004.
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    45. Hanus, M., et al. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders. Curr Med Res Opin. 20(1):63-71, 2004.
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    54. Poleszak, E., et al. Benzodiazepine/GABA(A) receptors are involved in magnesium-induced anxiolytic-like behavior in mice. Pharmacol Rep. 60(4):483-489, 2008.
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    59. Jobin Mathew,Savitha Balakrishnan, Sherin Antony, Pretty Mary Abraham, and CS Paulose; Decreased GABA receptor in the cerebral cortex of epileptic rats: effect ofBacopa monnieriand Bacoside-A: J Biomed Sci. 2012; 19(1): 25.
    60. Hoosain SJ, Aoshima H, Kiso Y. fragrances in oolong tea that enhance the response of GABA A receptors. Biosci Biotechnol Biochem. 2004 Sep;68(9): 1842 – 8.
    61. Cho YR, Chang JY, Chang HC. Production of GABA byte Lactobacillus buchneri isolated from kimchi and its neuro protective effect on neuron cells J Microbiol Biotechnol. 2007 Jan;17(1):104-9
    62. Inoue K, Shirai T, Ochiai H, Kassao M, Hayakawa K, Kimura M, Sansawa H. Blood pressure lowering effect of a novel fermented milk containing in mild hypertensives. J Clin Nutr. 2003 Mar; 57 (3):490-5
    63. Kim JY, Lee MY, Ji GE, Lee YS, Hwang KT. Reduction of GABA black raspberry juice during fermentation by Lactobacillus brevis. Int J Food Microbiol. 2009 Mar 15;130 (1):12-6.
    64. LI Y, Bai Q, Jin X, Wen H, Gu Z. Effects of cultivar and culture conditions on GABA accumulation in germinated fava beans. J Sci Food Argric. 2010 Jan 15;90(1):52-7
    65. Akihiro T, Koike S, Tani R, Tominaga T, Watanabe S, Iijima Y, Aoki K, Shibata D, Ashihara H, Matsukura C, Akama K, Fujimura T, Ezura H. Biochemical mechanisms of GABA accumulation during fruit development in tomato. Plant Cell Physiol. 2008 Sept;49(9): 1378-89.
    66. Kathiresan A, Tung P, Chinnappa CC, Reid DM. GABA stimulate ethylene biosynthesis in sunflower. Plant Physiol. 1997 Sept; 115 (1):129-35
    67. Avallone R, Zanoli P, Corsi L, Cannazza G, Baraldi M. Benzodiazepine compounds and GABA in flower heads of matricaria chamomilla. Phytotherapy Res. 1996;10:177–179.
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    69. Wang DS, Xu TL, Li JS. 5-HTP potentiates GABA- and glycine-activated chloride currents on the same neurons in rat spinal cord. J Hirnforsch. 1999;39(4):531-7.
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    74. Santos, M. S., et al. Synaptosomal GABA release as influenced by valerian root extract--involvement of the GABA carrier. Arch Int Pharmacodyn. 327(2):220-231, 1994.
    75. Muller, W. E., et al. Hyperforin - antidepressant activity by a novel mechanism of action. Pharmacopsychiatry. 34(Supplement 1):S98-S102, 2001.
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    Is Leaky Gut Syndrome Leaving You Feeling Unwell?

    These references are noted on our health article Is Leaky Gut Syndrome Leaving You Feeling Unwell?

    1. Sung Hee Lee: Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases Intest Res. 2015 Jan; 13(1): 11–18.
    2. Mark E. M. Obrenovich, Leaky Gut, Leaky Brain? Microorganisms. 2018 Dec; 6(4): 107.
    3. Alessandro Attanzio, Luisa Tesoriere, Sonya Vasto, Anna Maria Pintaudi, Maria A. Livrea, and Mario Allegra. Short-term cactus pear [Opuntia ficus-indica (L.) Mill] fruit supplementation ameliorates the inflammatory profile and is associated with improved antioxidant status among healthy humans. Food Nutr Res. 2018; 62: 10.29219/fnr.v62.1262.
    4. Sofia Moran-Ramos, Xuan He, Elizabeth L. Chin, Armando R. Tovar, Nimbe Torres, Carolyn M. Slupsky, and Helen E. Raybould; Nopal feeding reduces adiposity, intestinal inflammation and shifts the cecal microbiota and metabolism in high-fat fed rats. PLoS One. 2017; 12(2): e0171672.
    5. Erika Utzeri, Paolo Usai. Role of non-steroidal anti-inflammatory drugs on intestinal permeability and nonalcoholic fatty liver disease. World J Gastroenterol. 2017 Jun 14; 23(22): 3954–3963.
    6. Julia König, Jerry Wells, Patrice D Cani, Clara L García-Ródenas, Tom MacDonald, Annick Mercenier, Jacqueline Whyte, Freddy Troost, and Robert-Jan Brummer. Human Intestinal Barrier Function in Health and Disease. Clin Transl Gastroenterol. 2016 Oct; 7(10): e196.

    Is Pyroluria or Pyrrole Disorder Getting You Down? 

    These references are noted on our health article Is Pyroluria or Pyrrole Disorder Getting You Down?

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